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Advanced treatment

TIL (tumour-infiltrating lymphocyte therapy)

Cell therapy that expands lymphocytes already present inside the patient's tumour, then returns them after preparatory treatment.

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Ilustrasi alur terapi TIL dari pengambilan sel imun hingga infus kembali
Terapi selulerDraft, not yet medically reviewed

Not a diagnosis and not final medical advice. Must be reviewed by a doctor.

What is it?

In TIL, the patient's tumor tissue is used to obtain lymphocyte cells that recognize the tumor.

The cells are multiplied in the laboratory, then given back after preparatory therapy which is lymphodeplex.

This approach has been primarily studied in certain solid tumors, including melanoma and some cervical and lung cancers, and is still in the clinical research phase in many indications.

Lymphocytes taken from tumor tissue are multiplied in the laboratory and activated, then returned to the patient to attack tumor cells.
How TIL (tumour-infiltrating lymphocyte therapy)

How it works

Lymphocytes taken from tumor tissue are multiplied in the laboratory and activated, then returned to the patient to attack tumor cells.

Position in the treatment pathway: Generally only through clinical trials or special programs, usually after standard therapy no longer produces results.

Ilustrasi alur terapi TIL dari pengambilan sel imun hingga infus kembali

Which cancers is it usually discussed for?

Usually considered

  • Tumor tissue that can be accessed to obtain cells.
  • Organ conditions that allow preparatory therapy and monitoring.
  • Compliance with ongoing study criteria.

Usually not a candidate

  • There is not sufficient tumor tissue to obtain cells.
  • A medical condition that makes the procedure unacceptable.
  • There are no programs or studies available.

What is the process like?

  1. Preparation 1

    Removal of tumor tissue.

  2. Preparation 2

    Evaluation of organs and infection.

  3. Preparation 3

    Preparatory therapy planning.

  4. Monitoring

    Close monitoring after infusion.

All preparation

  • Removal of tumor tissue.
  • Evaluation of organs and infection.
  • Preparatory therapy planning.

All monitoring

  • Close monitoring after infusion.
  • Monitoring infection and blood cell recovery.
  • Evaluate response.

Risks and points to watch

Side-effect notes, not a complete list

This list covers categories commonly discussed. Individual risk is always assessed by the treating team.
  • Immune system related reactions may occur.
  • Infection and decreased blood cells during the recovery period.

Cost and access

Cost figures depend heavily on location, facility and payer. We do not show estimated figures on this page; what can be prepared first are the questions.

Treatment cost toolCost information centreCara meminta perkiraan biaya pengobatan: dokumen dan informasi yang diperlukan

Providers and clinical trials

Access status not yet verified

Studies are filtered from the public registry. Site readiness and international patient acceptance still need confirmation before any travel is planned.

NO DATA

No studies in the latest registry data mention this treatment category in their description.

View all studies in this categoryExplore hospitals

Questions for the doctor

  • Is there a TIL clinical trial that is appropriate for my condition?
  • What is the tissue collection process and how long does it take to prepare?
  • How is monitoring after infusion carried out?

Sources

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