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Decision situations

Start with your situation, not only the disease name

These pages address questions that arise at specific points in the disease journey, such as after surgery, when targeted therapy stops working, or when brain lesions are found.

Lung Cancer

Cancer page
  • Newly diagnosed

    Newly diagnosed lung cancer

    The initial stage after diagnosis is not choosing a drug, but rather ensuring the diagnosis, histology type, stage and complete biological markers.

    I just received a diagnosis of lung cancer. What do you need to confirm first?

  • Still operable

    Lung cancer that is still operable

    At a stage that is still operable, the discussion centers on the appropriateness of the procedure, the type of surgery, and whether additional therapy is needed afterwards.

    My tumor was assessed as operable. What to consider before and after?

  • Locally advanced

    Locally advanced lung cancer

    In locally advanced disease, discussions often combine radiotherapy and systemic therapy, with the sequence depending on the condition and markers.

    My disease is locally advanced and has not spread far. What options are usually discussed?

  • Metastatic disease

    Metastatic lung cancer

    In metastatic disease, biomarkers and general condition are the primary determinants of therapy category, and clinical trials are often part of the discussion.

    My disease has spread. How are therapy options usually structured?

  • Oligometastatic

    Oligometastatic lung cancer

    When spread is limited to a few locations, discussions may include local therapy targeted at the lesion, often in conjunction with systemic therapy.

    My deployment is limited to a few locations. Are local measures still being discussed?

  • After surgery

    After lung cancer surgery

    After surgery, pathology results and lymph node involvement determine whether additional therapy is discussed and how closely monitoring is performed.

    The operation is complete. What determines the next step?

  • Progression after targeted therapy

    Lung cancer progression after targeted therapy

    After progression to targeted therapy, re-examination of tissue or blood is usually considered to look for resistance mechanisms before selecting the next step.

    Targeted therapy no longer works. What is usually checked first?

  • Progression after immunotherapy

    Lung cancer progression after immunotherapy

    After progression to immunotherapy, it is necessary to determine whether what is occurring is true progression, an unusual response, or side effects related to the immune system.

    Immunotherapy no longer controls the disease. What needs to be assessed?

  • Spread to the brain

    Lung cancer with spread to the brain

    Brain involvement changes therapeutic considerations as it influences symptoms, the choice of drugs that penetrate the blood-brain barrier, and the feasibility of targeted radiotherapy.

    There is a lesion in the brain. How does this change the therapy plan?

  • Spread to bone

    Lung cancer with spread to the bones

    Spread to the bone can cause pain and increase the risk of fracture, so local treatment and supportive medications are part of the plan.

    There is spread to the bones. What to consider?

Stomach Cancer

Cancer page
  • After chemotherapy is no longer effective

    Gastric cancer after chemotherapy no longer gives results

    In gastric cancer, the next steps depend on markers such as HER2, PD-L1, MSI/MMR, and CLDN18.2, as well as on the history of previous therapy.

    Chemotherapy no longer works on my stomach cancer. What's the next step?

Breast Cancer

Cancer page
  • Spread to the brain

    Lung cancer with spread to the brain

    Brain involvement changes therapeutic considerations as it influences symptoms, the choice of drugs that penetrate the blood-brain barrier, and the feasibility of targeted radiotherapy.

    There is a lesion in the brain. How does this change the therapy plan?

  • Spread to bone

    Lung cancer with spread to the bones

    Spread to the bone can cause pain and increase the risk of fracture, so local treatment and supportive medications are part of the plan.

    There is spread to the bones. What to consider?

  • Progression after targeted therapy

    Breast cancer progression after HER2 therapy

    After progression on HER2 therapy, HER2 status can be reassessed and the next choice depends on the sequence of therapy undertaken and the location of spread.

    Anti-HER2 therapy no longer controls the disease. What needs to be reassessed?

Not a diagnosis and not final medical advice. Must be reviewed by a doctor.

Next steps

These suggestions come from links between entries in TanyaKanker's database, not from a medical judgement. Each suggestion includes why it appears.

Next to learn

  • Lung Cancer

    Cancer type

    Reason: Most connected in the oncology graph

  • Stomach Cancer

    Cancer type

    Reason: Most connected in the oncology graph

  • Lymphoma

    Cancer type

    Reason: Most connected in the oncology graph

  • Multiple Myeloma

    Cancer type

    Reason: Most connected in the oncology graph

  • ALK

    Biomarker

    Reason: Highest discovery priority among markers

  • BCMA

    Biomarker

    Reason: Highest discovery priority among markers

  • BCR-ABL

    Biomarker

    Reason: Highest discovery priority among markers

  • BRAF

    Biomarker

    Reason: Highest discovery priority among markers

To check

What you can do

  • Upload medical reports

    Build a case summary in twelve steps

    Reason: Often the most useful next step after reading this page

  • Request a second opinion

    Review of the treatment plan

    Reason: Relevant when a treatment plan is being considered

  • Consult a navigator

    A request is recorded with this page context

    Reason: For asking the next step directly

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