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Metastatic diseaseLung Cancer

Metastatic lung cancer

My disease has spread. How are therapy options usually structured?

In metastatic disease, biomarkers and general condition are the primary determinants of therapy category, and clinical trials are often part of the discussion.

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Not a diagnosis and not final medical advice. Must be reviewed by a doctor.

What changes at this stage

  • The general goal of therapy is to control the disease and maintain quality of life.
  • Biological markers determine whether targeted therapy is relevant.
  • The history of previous therapy determines the order of subsequent choices.

Options that are usually discussed

  • Systemic therapy based on markers

    If actionable markers are found, the target therapy category becomes the main discussion.

  • Immunotherapy, alone or in combination

    The relevance of immunotherapy is assessed by markers such as PD-L1 as well as the patient's condition.

  • Clinical trials

    Ongoing studies are often discussed when standard options are limited or have already been explored.

The decision remains with your doctor

This page explains the options that may be discussed; it does not choose one for you.

Practical next steps

  • Make sure all marker results are available in the form of a complete report.
  • Ask how many lines of therapy have been undertaken and what the response has been.
  • Assess suitability for the clinical trial that is recruiting participants.

Questions for your oncologist

  • What are the goals of therapy at this stage and how is its success assessed?
  • Which markers should I base my therapy choices on?
  • What options are available if this therapy no longer works?
  • Are there any clinical trials that might be appropriate?

Relevant biomarkers

Treatment categories

Drugs commonly discussed

Supporting guides

Clinical trials

Registry studies for this group

International-patient access and site readiness have not been verified for any study.

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