EGFR lung cancer
Osimertinib is no longer working: what should be checked next?
Progression after osimertinib usually needs to be considered with scan changes, disease sites, treatment history, and the latest molecular testing.
This may be relevant if
- A CT or PET report shows changes after Tagrisso.
- A doctor mentioned EGFR progression or resistance.
- You want to prepare questions about repeat testing, trials, or a second opinion.
What information matters?
Start with what you have. Missing information can be marked and completed later.
- The latest scan and its comparison report
- Available EGFR, NGS, or pathology results
- Osimertinib and other treatment history
- Sites of change and the main question
A practical next step
- 1Save scans, pathology, and treatment history in the Cancer Passport.
- 2Note whether the change is limited to one site or appears in several sites.
- 3Ask whether tissue testing, NGS, or liquid biopsy may help clarify resistance.
- 4Request a review to discuss other treatments, trials, or a second opinion.
Not a diagnosis and not final medical advice. Must be reviewed by a doctor.
Review a case after osimertinib progression
Bring scans, molecular results, and treatment history together so questions for a navigator are more focused.
After submission, a human navigator reviews your request and contacts you through your chosen channel. The WhatsApp message already includes this page context, so you do not need to explain from the beginning.
Clinical data is not requested in the form and is not sent to analytics. Do not send medical reports through WhatsApp or email; use the secure upload page. We do not promise eligibility or any treatment outcome.
Continue exploring
Use a case summary, not a copied medical history
The Cancer Passport keeps the information you choose to save in one place so a later review can start from the same context.
Ready to take the next step?
Start with the information you have. A navigator can help identify what to review next.
Prepare for your next consultation
Use the free six-question tool to prepare questions for your doctor.