BCMA positive
BCMA expression on plasma cells, required when discussing anti-BCMA therapy.
Parent marker: BCMA
Not a diagnosis and not final medical advice. Must be reviewed by a doctor.
Clinical meaning
BCMA has been targeted by bispecific antibody and cellular therapy in multiple myeloma that has undergone multiple lines of therapy.
How this finding appears in a report
Assessed from the bone marrow via immunohistochemistry or cell flow.
When therapy stops working
Loss of BCMA expression or decreased levels may occur after previous therapy, including anti-BCMA therapy.
What needs verification
- Complete variant name as written in the laboratory report.
- Examination methods and types of samples used.
- Examination dates were compared with ongoing therapy.
Marker context: BCMA
BCMA expression is a consideration in cellular therapy and bispecific antibodies for multiple myeloma that has undergone several lines of therapy.
A negative result does not always mean absent
Summary
- Gen
- TNFRSF17
- Variant
- BCMA expression positive
- Alteration type
- Immunophenotype
- Discussed in
- Multiple Myeloma
- Updated
- 2026-09-10
Other names in reports
BCMA+
Treatment categories
Sources
- NCI Dictionary of Cancer Terms(lembaga)
- ClinicalTrials.gov(registry)
Next steps
These suggestions come from links between entries in TanyaKanker's database, not from a medical judgement. Each suggestion includes why it appears.
Next to learn
- BCMA
Biomarker
Reason: Related through a biomarker
- Multiple Myeloma
Cancer type
Reason: Related to this page
- Belantamab mafodotin
Drug
Reason: Related to this page
- Ciltacabtagene autoleucel
Drug
Reason: Related to this page
- CAR-T (chimeric antigen receptor T-cell therapy)
Treatment category
Reason: Related to this page
- Immunotherapy
Treatment category
Reason: Related to this page
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