FLT3
Other names: FLT3-ITD, FLT3-TKD, FLT3 mutation
Changes in the FLT3 gene are findings often discussed in acute myeloid leukemia.
Not a diagnosis and not final medical advice. Must be reviewed by a doctor.
Plain explanation
FLT3 is a gene that regulates blood cell growth. Changes in these genes can make leukemia cells grow faster and affect how therapy is discussed.
Clinical meaning
FLT3 mutations, especially FLT3-ITD, are among the markers examined in acute myeloid leukemia and open the category of FLT3 inhibitors in some therapeutic situations.
Testing methods
- Next-generation sequencing (NGS)
A test that reads many genes from one tumour sample to find actionable changes.
- Bone marrow biopsy and aspiration
Collection of bone marrow to assess plasma cells and blood production.
A negative result does not always mean the marker is absent
Test sensitivity differs by sample type and method. Results need to be read together with the pathology report and clinical condition.
What needs verification
- Types of FLT3 alterations found and their allelic ratios when reported.
- Recent bone marrow examination and current disease status.
- History of previous therapy, including whether you have received an FLT3 inhibitor.
Related drugs
- Midostaurin
Multi-kinase FLT3 inhibitor
- Gilteritinib
FLT3 inhibitor
A link here means the marker is often part of considering a drug category, not a recommendation to use it.
Clinical trials
Studies mentioning this marker
Filtered from public study descriptions. Access status and site readiness remain unverified.
NO DATA
No studies in the latest registry data mention this marker in their description.
Check options based on your result
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Next steps
These suggestions come from links between entries in TanyaKanker's database, not from a medical judgement. Each suggestion includes why it appears.
Next to learn
- Leukemia
Cancer type
Reason: Related through a biomarker
- FLT3-ITD
Molecular alteration
Reason: Related through a biomarker
- Targeted therapy
Treatment category
Reason: Related through a biomarker
- Gilteritinib
Drug
Reason: Targets this marker
- Midostaurin
Drug
Reason: Targets this marker
To check
- Bone marrow biopsy and aspiration
Diagnostic test
Reason: Diperiksa melalui
- Next-generation sequencing (NGS)
Diagnostic test
Reason: Diperiksa melalui
- Check medical report completeness
Tool
Reason: Prepare documents that still need confirmation
- Prepare questions for your doctor
Tool
Reason: Bring clear questions to the next conversation
What you can do
- Upload medical reports
Build a case summary in twelve steps
Reason: Often the most useful next step after reading this page
- Request a second opinion
Review of the treatment plan
Reason: Relevant when a treatment plan is being considered
- Consult a navigator
A request is recorded with this page context
Reason: For asking the next step directly
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